- What Is NAD+ Cell Energy Vitamin?
- Why NAD+ Levels Decline and How Your Body Changes
- How NAD+ IV Drip Works
- Who It's For & Who Should Consult First
- NAD+ IV vs. Oral Vitamin Supplements
- How Many Sessions Before You Notice a Change
- Safety and Side Effects
- Aftercare
- Pricing and Packages
- NAD+ IV in Phitsanulok — Depry Clinic
- Frequently Asked Questions
- References
NAD+ cell energy vitamin is a coenzyme every cell uses to produce energy and repair DNA. As we age, NAD+ levels decline, which may affect fatigue, brain fog, and slow recovery. Replenishing NAD+ via intravenous drip (IV Drip) is one option that may help cells use it directly. At Depry Clinic in Phitsanulok, this service is available — 250 mg dose starts at 7,900 THB/session, with a 5-session package at 29,900 THB
What Is NAD+ Cell Energy Vitamin?
Many people see the term NAD+ and wonder how it differs from the vitamins they usually take. In reality, NAD+ is not an ordinary vitamin pill — it is a coenzyme (Coenzyme) that the body can produce itself from vitamin B3 (Niacin), and it is found in nearly every cell type in the body
I often hear patients tell me, "I've been taking multivitamins for months and I'm still tired." The truth is, NAD+ performs two vital roles at the cellular level:
- Produces ATP energy — acts as an intermediary in the mitochondria (the cell's power plant). Cells that work hard — such as the brain, heart, and muscles — need a lot of NAD+
- Repairs DNA — works with sirtuin and PARP enzymes involved in repairing genetic material
NAD+ has always been in our bodies — so why do we need to replenish it?
The short answer is — NAD+ levels decline with age. Multiple studies report that by age 50, NAD+ levels in the body may be only half of what they were at age 20. The more stress, the less sleep, and the more alcohol — the faster it declines
NAD+ is not a disease treatment, and it is not a "miracle vitamin" that will transform your life in a single session. It is one option that may help cells function at a higher level. Whether it's right for you — I'll help assess that precisely
Why NAD+ Levels Decline and How Your Body Changes
Got questions? Dr. Time offers personalized, honest consultations — no upselling.
Consult Dr. TimeIf one day you feel like you "get tired more easily, your brain isn't as sharp, and you recover more slowly" — even though your health checkup comes back normal — one explanation researchers are studying is declining NAD+ levels
3 Factors That Speed Up NAD+ Decline
- Increasing age — the enzymes that produce NAD+ work less, while the enzymes that break down NAD+ work more
- Chronic stress + lack of sleep — the body uses more NAD+ to repair cells damaged by oxidative stress
- Frequent alcohol consumption — the liver must use NAD+ directly in alcohol metabolism
"I wake up feeling unrefreshed" · "Brain fog, slow thinking" · "Soreness after exercise lasts longer" · "Recovering from colds takes longer than before" — these four symptoms are common in people who may have lower NAD+ levels. But I emphasize these symptoms can have many other causes and must be assessed case by case
How NAD+ IV Drip Works
I'll explain it as simply as possible — NAD+ enters the bloodstream directly, bypassing the digestive process in the stomach. Cells can therefore use it immediately
Procedure Steps (Overview)
- Doctor consultation — health history screening, contraindications check, and goal assessment
- Prepare the NAD+ solution — standard 250 mg dose mixed in sterile normal saline
- IV drip administration — takes about 2 hours, allowing the body to absorb it comfortably without facial flushing or nausea
- Observation period — about 15–30 minutes after the drip finishes, before going home
If the drip is too fast, NAD+ over-stimulates the body's receptors, which may cause nausea, flushing, or chest tightness. A slow, steady drip lets the body adjust — side effects are significantly reduced
Why IV rather than oral pills?
I get this question a lot. The answer is that when NAD+ is taken orally, it gets digested in the stomach and liver, so very little reaches the cells. With IV delivery, it enters the bloodstream directly and cells can use it at full efficiency
Who It's For & Who Should Consult First
Suitable For
- People who feel chronically fatigued and wake up unrefreshed
- Hard workers with brain fatigue and poor concentration
- People recovering slowly after illness or post-Long Covid
- Biohackers / those focused on preventive health
- People who want to support cellular function in the long term
Should Consult a Doctor First
- People with heart, kidney, or liver conditions
- Those who are pregnant or breastfeeding
- Those taking blood thinners or blood pressure medication
- Those with a history of allergy to vitamin B3 or NAD
NAD+ IV vs. Oral Vitamin Supplements
Many people ask me, "Can I just take a lot of vitamin B3 instead?" I understand the reasoning, but the mechanisms differ:
| Topic | NAD+ IV Drip | Vitamin B3 Pills (Niacin) |
|---|---|---|
| Absorption | Enters the bloodstream directly | Passes through the stomach and liver before reaching cells |
| Amount reaching cells | Close to 100% | Little remains after metabolism |
| Speed of perceptible effect | Gradually accumulates with consistent sessions | Depends on body condition |
| Side effects | Mild warmth during drip, slight nausea | Flushing and itch from niacin |
| Suitable for | Those who want to replenish cellular levels directly | General long-term nutritional support |
NAD+ IV is not a replacement for general nutritional vitamins, but rather a complementary option for people who want to replenish NAD+ at the cellular level directly. I usually recommend taking oral vitamins alongside it for long-term maintenance
Real-world price comparison: NAD+ IV clinics in Bangkok offering a 250 mg dose in a 5-session package charge roughly 36,000 THB. At Depry Clinic in Phitsanulok, the same package is 29,900 THB — same dose, supervised by a physician, and no long-distance travel required
How Many Sessions Before You Notice a Change
I'll answer this question directly — you won't see results from a single session, because NAD+ replenishes cellular levels gradually, not instantly
Typical Course Recommendations
- Start with 1 session at 250 mg to observe how your body responds
- 5-session package acts as a loading phase where many people begin to notice changes (typically 1–2 sessions per week)
- 10-session package for those who want long-term cellular health support (VIP / longevity)
Perceptible results vary for each person — they depend on age, body condition, sleep, and stress levels. I'll assess precisely how many sessions you should start with, then adjust based on your response
Safety and Side Effects
NAD+ is a substance already present in the body naturally — it is not a novel synthetic compound. Replenishment via IV under a doctor's supervision therefore carries a relatively low risk
Possible Side Effects
- Mild warmth during the drip — common; resolves when the drip speed is adjusted
- Slight nausea — usually occurs early in the drip; sipping water slowly helps
- Mild headache — uncommon; resolves on its own within 1–2 hours
- Bruising from the needle — a normal occurrence with venous access
People with underlying medical conditions — especially heart, kidney, or liver disease, or who are pregnant — must inform the doctor every time. I'll assess whether it's appropriate; not everyone is a candidate
Aftercare for NAD+ IV
After your NAD+ IV session, your body doesn't require extensive special care. But I recommend these four points to help the replenishment last longer:
1. Drink plenty of plain water
After the drip finishes, drink 500 ml to 1 litre of plain water in the first 1–2 hours to help your body distribute NAD+ to cells more effectively
2. Avoid alcohol for at least 24–48 hours
Alcohol uses NAD+ directly in metabolism, reducing the effectiveness of the replenishment
3. Get enough sleep
Sleeping 7–8 hours allows cells to repair themselves fully — this is when cells use NAD+ the most
4. Light exercise the next day
No need for extensive rest, but avoid intense exercise in the first 24 hours. Gradually return to your normal routine
NAD+ IV replenishes cellular levels. How long the effects last depends on your post-treatment lifestyle too. If you sleep well, eat well, and manage stress, the benefits last longer than for those who stay up late or drink alcohol frequently
Pricing and Packages
At Depry Clinic in Phitsanulok, pricing is divided into 3 tiers — choose based on your goals and budget:
| Package | Price | Average / Session | Suitable For |
|---|---|---|---|
| Single Session (First-Time Trial) | 7,900 THB | 7,900 THB | Want to try first and observe your body's response |
| 5-Session Package | 29,900 THB | 5,980 THB | Beginning to see changes (recommended) |
| 10-Session Package | 54,900 THB | 5,490 THB | VIP / longevity long-term support |
NAD+ IV is not inexpensive, because the actual drug cost is high and the drip itself takes 2 hours. I chose to offer the 5-session package as the primary option because most people need consistent sessions before they truly feel a difference
Want to upgrade to 500 mg (2 vials)? After your body has adjusted to the 250 mg dose, you can upgrade to 500 mg for just 3,900 THB more per session for stronger effects. I'll help assess when you're ready to step up the dose
NAD+ IV in Phitsanulok — Depry Clinic
If you're in Phitsanulok or nearby provinces such as Phichit, Sukhothai, Uttaradit, Kamphaeng Phet, or Phetchabun — and you're looking for an NAD+ IV service supervised by an experienced doctor — Depry Clinic is one of the few places in the lower Northern region that offers this service
I personally oversee every case — from history taking, contraindications screening, and dose assessment, through to post-treatment care. Many patients travel from other provinces because we offer a full 2-hour slow NAD+ IV drip — not a quick injection with just saline solution
I hold a Board Certification in Anti-Aging Medicine (ABAARM, USA) and Aesthetic Medicine (AAAM, USA), with a doctorate from the University of Leeds, UK. I'm ready to consult with you and design an NAD+ program tailored to your body — especially with gradual dose adjustment based on your body's response, for the safest and most effective results
NAD+ IV requires up to 2 hours per person in a private drip room, so we accept a limited number of appointments per day. We recommend booking at least 2–3 days in advance. If you're interested, you can view more details and book through the NAD+ IV Therapy page
What's Included in Every Case: Free screening and consultation with the doctor before starting the program · Drip in a private room (full rest during the session) · Follow-up after each session to adjust the dose based on your response
Frequently Asked Questions
1. How often should I do NAD+ IV?
It depends on your goals. During the loading phase, 1–2 sessions per week is recommended for 4–5 consecutive weeks. After that, you can do once a month to maintain levels
2. Do I need to rest after NAD+?
No downtime is needed. After the drip finishes, observe for 15–30 minutes and you can head home. You can resume your daily routine normally
3. How is NAD+ IV different from Glutathione injections?
They differ. Glutathione is an antioxidant focused on brightening the skin. NAD+ is an energy coenzyme focused on cellular recovery and brain function. Different goals. Some people combine both, but you should consult a doctor first
4. Can I drink alcohol after NAD+?
Not recommended. Alcohol uses NAD+ in metabolism, which reduces the effectiveness of the replenishment. I recommend abstaining for 24–48 hours after the session
5. Does NAD+ help with insomnia?
It's not a sleeping pill. However, many patients report that after a consistent course, they fall asleep more easily — because their body recovers better and the brain isn't overly stimulated at night
6. If I have an underlying condition, can I still do NAD+?
It depends on the type of condition and the medications you're taking. I'll assess on a case-by-case basis. People whose conditions are well-controlled and who have no contraindications can usually proceed — but you must inform the doctor every time
7. Does NAD+ IV have FDA (Thai FDA) registration?
The NAD+ drug we use is imported by Gibthai and is registered with the Thai FDA. The clinic providing the service must hold a healthcare facility operating license and operate under a physician
8. How long do results last after I stop?
NAD+ levels gradually decline again following the natural aging process. I recommend periodic sessions or maintaining a long-term supportive course, depending on each person's goals
References
Here are the sources I used to write this article — click through to verify the originals:
- NCBI / PubMed Central — Review article on NAD+ in the aging process and NAD+ replenishment in animal models: pmc.ncbi.nlm.nih.gov
- Cleveland Clinic — Article explaining the role of NAD+ and NAD+ supplements in the body: my.clevelandclinic.org
- NCBI / PubMed Central — Clinical Research Review — Systematic Review and Meta-analysis on the effects of NAD+ precursors (NR/NMN) in humans — metabolism, brain, and heart: pmc.ncbi.nlm.nih.gov
- Thai Food and Drug Administration (FDA) — Verification system for drug registration numbers and health products in Thailand: oryor.com
- Harvard Health Publishing — Article on NAD+ precursors (NMN, NR) and clinical research: health.harvard.edu
